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microbiome norvius secretor
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Publication:10.1093/ofid/ofac125 PDF: Available

Association of Secretor Status and Recent Norovirus Infection With Gut Microbiome Diversity Metrics in a Veterans Affairs Population

Jordan A Johnson, Timothy D Read, Robert A Petit III, Vincent C Marconi, Kathryn L Meagley, Maria C Rodriguez-Barradas, David O Beenhouwer, Sheldon T Brown, Mark Holodniy, Cynthia A Lucero-Obusan, Patricia Schirmer, Jessica M Ingersoll, Colleen S Kraft, Frederick H Neill, Robert L Atmar, Anita K Kambhampati, Jordan E Cates, Sara A Mirza, Aron J Hall, Cristina V Cardemil, Benjamin A Lopman

Abstract

Norovirus infection causing acute gastroenteritis could lead to adverse effects on the gut microbiome. We assessed the association of microbiome diversity with norovirus infection and secretor status in patients from Veterans Affairs medical centers. Alpha diversity metrics were lower among patients with acute gastroenteritis but were similar for other comparisons.

Citation

Johnson, J. A., Read, T. D., Petit, R. A., 3rd, Marconi, V. C., Meagley, K. L., Rodriguez-Barradas, M. C., Beenhouwer, D. O., Brown, S. T., Holodniy, M., Lucero-Obusan, C. A., Schirmer, P., Ingersoll, J. M., Kraft, C. S., Neill, F. H., Atmar, R. L., Kambhampati, A. K., Cates, J. E., Mirza, S. A., Hall, A. J., Cardemil, C.V., & Lopman, B. A. Association of Secretor Status and Recent Norovirus Infection With Gut Microbiome Diversity Metrics in a Veterans Affairs Population. Open Forum Infectious Diseases, 9(5), ofac125. (2022)